Effect of Chronic Kidney Disease on Nonrenal Elimination Pathways: A Systematic Assessment of CYP1A2, CYP2C8, CYP2C9, CYP2C19, and OATP

Author:

Tan Ming-Liang1,Yoshida Kenta12,Zhao Ping1,Zhang Lei1,Nolin Thomas D.3,Piquette-Miller Micheline4,Galetin Aleksandra5,Huang Shiew-Mei1

Affiliation:

1. Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research; U.S. Food and Drug Administration; Silver Spring Maryland USA

2. Current affiliation: Clinical Pharmacology; Genentech Research and Early Development; South San Francisco California USA

3. Center for Clinical Pharmaceutical Sciences, Department of Pharmacy and Therapeutics, and Department of Medicine Renal-Electrolyte Division; University of Pittsburgh Schools of Pharmacy and Medicine; Pittsburgh Pennsylvania USA

4. Leslie Dan Faculty of Pharmacy; University of Toronto; Toronto Ontario Canada

5. Centre for Applied Pharmaceutical Research, School of Heath Sciences; University of Manchester; Manchester UK

Funder

US Food and Drug Administration's (FDA's) Medical Countermeasures Initiative

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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