Predicting human plasma protein binding of drugs using plasma protein interaction QSAR analysis (PPI-QSAR)

Author:

Li Haiyan1,Chen Zhuxi1,Xu Xuejun1,Sui Xiaofan2,Guo Tao1,Liu Wei3,Zhang Jiwen

Affiliation:

1. Center for Drug Delivery System; Shanghai Institute of Materia Medica, State Key Laboratory of Drug Research, Chinese Academy of Sciences; Shanghai; 201203; China

2. Liaoning Provincial Institute for Drug and Food Control; Shenyang; 110023; China

3. School of Pharmacy; Shenyang Pharmaceutical University; Shenyang; 110016; China

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference28 articles.

1. Predicting plasma protein binding of drugs - revisited;Kratochwil;Curr Opin Drug Discov Devel,2004

2. Plasma/serum protein binding determinations;Banker;Curr Drug Metab,2008

3. Structure-ADME relationship: still a long way to go?;Hou;Expert Opin Drug Metab Toxicol,2008

4. Species differences of serum albumins: II. Chemical and thermal stability;Kosa;Pharm Res,1998

5. Species differences of serum albumins: I. Drug binding sites;Kosa;Pharm Res,1997

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