Localised erythema nodosum leprosum—A rare entity managed with thalidomide-Reference-Cited by-同舟云学术

Localised erythema nodosum leprosum—A rare entity managed with thalidomide

Published:2024-02-07 Issue:2 Volume:4 Page:
ISSN:2690-442X
Container-title:Skin Health and Disease
language:en
Short-container-title:Skin Health and Disease

Author:

Patel Chandni¹^ORCID,De Barros Barbara²³^ORCID,Walker Stephen L.²³⁴^ORCID

Affiliation:

1. Department of Healthcare Services for Elderly People Royal Free Hospital NHS Foundation Trust London UK

2. Hospital for Tropical Diseases University College London Hospitals NHS Foundation Trust London UK

3. Faculty of Infectious and Tropical Diseases London School of Hygiene and Tropical Medicine London UK

4. Department of Dermatology University College London Hospitals NHS Foundation Trust London UK

Abstract

AbstractLeprosy is caused by Mycobacterium leprae. The condition primarily affects the skin and peripheral nerves. There are two types of leprosy reactions, Type 1 and Type 2 or erythema nodosum leprosum (ENL). ENL is a severe multi‐system, immune‐mediated complication of lepromatous leprosy. It is characterised by widespread painful cutaneous nodules, fever and peripheral oedema. This report discusses the unusual case of a 29‐year‐old woman who developed a localised form of ENL which required thalidomide to induce remission.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ski2.339

Reference15 articles.

1. A leprosy clinical severity scale for erythema nodosum leprosum: An international, multicentre validation study of the ENLIST ENL Severity Scale

2. A Systematic Review of Immunological Studies of Erythema Nodosum Leprosum

3. ENLIST 1: An International Multi-centre Cross-sectional Study of the Clinical Features of Erythema Nodosum Leprosum