A possible aid in targeted insertion of large DNA elements by CRISPR/Cas in mouse zygotes

Author:

Nakao Harumi1,Harada Takeshi1,Nakao Kazuki12,Kiyonari Hiroshi23,Inoue Kenichi2,Furuta Yasuhide23,Aiba Atsu1

Affiliation:

1. Laboratory of Animal Resources, Center for Disease Biology and Integrative Medicine, Faculty of Medicine; The University of Tokyo; Bunkyo-Ku Tokyo 113-0033 Japan

2. Animal Resource Development Unit; Division of Bio-Function Dynamics Imaging, RIKEN Center for Life Science Technologies; Kobe Hyogo 650-0047 Japan

3. Genetic Engineering Team, Division of Bio-Function Dynamics Imaging; RIKEN Center for Life Science Technologies; Kobe Hyogo 650-0047 Japan

Funder

Ministry of Education, Culture, Sports, Science, and Technology

Publisher

Wiley

Subject

Cell Biology,Endocrinology,Genetics

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