Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the CDKN1A (p21WAF1 / CIP1 ) and SIRT1 genes-Reference-Cited by-同舟云学术

Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the CDKN1A (p21WAF1 / CIP1 ) and SIRT1 genes

Published:2015-02-02 Issue:1 Volume:236 Page:103-115
ISSN:0022-3417
Container-title:The Journal of Pathology
language:en
Short-container-title:J. Pathol.

Author:

Wu Dinglan¹,Yu Shan¹,Jia Lin¹,Zou Chang¹,Xu Zhenyu¹,Xiao Lijia¹,Wong Kam-Bo²,Ng Chi-Fai³,Chan Franky L¹

Affiliation:

1. School of Biomedical Sciences; Chinese University of Hong Kong, Hong Kong; People's Republic of China

2. School of Life Sciences; Chinese University of Hong Kong, Hong Kong; People's Republic of China

3. Department of Surgery; Chinese University of Hong Kong, Hong Kong; People's Republic of China

Funder

Research Grants Council, University Grants Committee, Hong Kong

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/path.4505/fullpdf

Reference54 articles.

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3. Cellular senescence: molecular mechanisms, in vivo significance, and redox considerations;Muller;Antioxid Redox Signal,2009

4. The senescence pathway in prostatic carcinogenesis;Sharma;Pathology,2010

5. Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence;Lin;Nature,2010

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