Modification of Diet to Reduce the Stemness and Tumorigenicity of Murine and Human Intestinal Cells

Author:

May Stephanie1,Greenow Kirsty R.1,Higgins Adam T.1,Derrick Anna V.1,Taylor Elaine1,Pan Pan2,Konstantinou Maria1,Nixon Colin3,Wooley Thomas E.4,Sansom Owen J.35,Wang Li‐Shu2,Parry Lee16ORCID

Affiliation:

1. European Cancer Stem Cell Research Institute School of Biosciences Cardiff University Cardiff CF24 4HQ UK

2. Division of Haematology and Oncology Medical College of Wisconsin 8701 Watertown Plank Rd Milwaukee WI 53226 USA

3. CRUK Beatson Institute Switchback Road, Bearsden Glasgow G61 1BD UK

4. School of Mathematics Cardiff University Senghennydd Road Cardiff CF24 4AG UK

5. Insitute of Cancer Sciences University of Glasgow Switchback Road, Bearsden Glasgow G61 1QH UK

6. Wales Cancer Research Centre University Hospital of Wales Room 1TB2 31, First Floor Main Building Cardiff CF14 4XN UK

Funder

World Cancer Research Fund

Publisher

Wiley

Subject

Food Science,Biotechnology

Reference28 articles.

1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

2. World Cancer Research Fund/American Institute for Cancer Research.Diet Nutrition Physical Activity and Cancer: A Global Perspective. Continuous Update Project Expert Report. A summary of the Third Expert Report 2018 https://www.wcrf.org/wp-content/uploads/2021/02/Summary-of-Third-Expert-Report-2018.pdf(accessed: November 2018.)

3. Crypt stem cells as the cells-of-origin of intestinal cancer

4. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

5. Black Raspberries Inhibit Intestinal Tumorigenesis in Apc1638+/− and Muc2−/− Mouse Models of Colorectal Cancer

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