Investigating the effects of norepinephrine α1 receptor blockade on dopamine levels: A pilot PET study with [11C]-(+)-PHNO in controls

Author:

Le Foll Bernard12345ORCID,Thiruchselvam Thulasi1,Lu Shawna Xiaoyun1,Mohammed Shakira1,Mansouri Esmaeil6,Lagzdins Dina6,Nakajima Shinichiro6,Wilson Alan A.6,Graff-Guerrero Ariel376,Di Ciano Patricia1,Boileau Isabelle8

Affiliation:

1. Translational Addiction Research Laboratory; Centre for Addiction and Mental Health; 33 Russell Street Toronto Ontario M5S 2S1 Canada

2. Alcohol Research and Treatment Clinic, Addiction Medicine Services, Ambulatory Care and Structured Treatments; Centre for Addiction and Mental Health; Toronto Ontario M6J 1H4 Canada

3. Campbell Family Mental Health Research Institute; Centre for Addiction and Mental Health; 33 Russell Street Toronto ON M5S 2S1 Canada

4. Department of Family and Community Medicine; University of Toronto; Canada

5. Department of Pharmacology; University of Toronto; Canada. Department of Psychiatry; University of Toronto; Canada. Division of Brain and Therapeutics; University of Toronto; Canada. Institute of Medical Sciences; University of Toronto; Canada

6. Research Imaging Centre; Centre for Addiction and Mental Health; 250 College Street Toronto Ontario M5T 1R Canada

7. Institute of Medical Sciences; University of Toronto; Canada

8. Addiction Imaging Research Group; Centre for Addiction and Mental Health; 250 College Street Toronto Ontario M5T 1R Canada

Funder

Lung Association

Canadian Foundation for Innovation

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience

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