Quantifying gut wall metabolism: methodology matters-Reference-Cited by-同舟云学术

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Quantifying gut wall metabolism: methodology matters

Published:2017-02-14 Issue:2 Volume:38 Page:155-160
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Hatley Oliver J.D.¹,Jones Christopher R.²,Galetin Aleksandra³,Rostami-Hodjegan Amin¹³^ORCID

Affiliation:

1. Simcyp Ltd (A Certara Company); Blades Enterprise Centre; Sheffield S2 4SU UK

2. DMPK; Heptares; Welwyn Garden City AL7 3AX UK

3. Centre for Applied Pharmacokinetic Research, Manchester Pharmacy School; University of Manchester; Manchester M13 9PT UK

Funder

Medical Research Council

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bdd.2062/fullpdf

Reference36 articles.

1. PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: prediction of plasma concentration-time profiles in human by using the physiologically-based pharmacokinetic modeling approach;Poulin;J Pharm Sci,2011

2. Enzymatic activities in the microsomes prepared from rat small intestinal epithelial cells by differential procedures;Mohri;Pharm Res,2001

3. Intestinal and hepatic metabolic activity of five cytochrome P 450 enzymes: impact on prediction of first-pass metabolism;Galetin;J Pharmacol Exp Ther,2006

4. Isolation and comparison of endoplasmic reticulum membranes and their mixed function oxidase activities from mammalian extrahepatic tissues;Burke;Pharmacol Ther,1979

5. Species differences in in vitro and in vivo small intestinal metabolism of CYP3A substrates;Komura;J Pharm Sci,2008

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4. Investigating the uncertainty of prediction accuracy for the application of physiologically based pharmacokinetic models to animal-free risk assessment of cosmetic ingredients;Regulatory Toxicology and Pharmacology;2022-11

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