Pharmacokinetic and Pharmacodynamic Profiles of Vapiprost, a Selective, Long-Lasting Thromboxane Receptor Antagonist, After Single and Multiple Oral Administration to Healthy Volunteers

Author:

Uematsu Toshihiko,Nagashima Satoru,Mizuno Atsuhiro,Hirano Keiko,Nakashima Mitsuyoshi

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference22 articles.

1. Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin;Moncada;Pharmacol Rev,1979

2. Overview of physiological and pathophysiological effects of thromboxane A2;Ogletree;Fed Proc,1987

3. Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides;Hamberg;Proc Natl Acad Sci USA,1975

4. In vitro and in vivo effects of new powerful thromboxane antagonists (3-alkylamino pinene derivatives);Katsura;Adv Prostaglandin Thromboxane Leukotriene Res,1983

5. Competitive antagonism at thromboxane receptors in human platelets;Armstrong;Br J Pharmacol,1985

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