Profibrotic transforming growth factor beta 1 and activin A are increased in nasal polyp tissue and induced in nasal polyp epithelium by cigarette smoke and Toll-like receptor 3 ligation
Author:
Affiliation:
1. Division of Rheumatology; Allergy & Immunology, Massachusetts General Hospital; Boston MA
2. Department of Otolaryngology; Massachusetts Eye & Ear Infirmary; Boston MA
Funder
Flight Attendant Medical Research Institute
Merck
Publisher
Wiley
Subject
Otorhinolaryngology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/alr.21516/fullpdf
Reference42 articles.
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2. The effect of transforming growth factor (TGF)-beta1 and (TGF)-beta2 on nasal polyp fibroblast activities involved upper airway remodeling: modulation by fluticasone propionate;Serpero;Immunol Lett,2006
3. Injury and epithelial wound healing: a pathophysiologic hypothesis for nasal and sinus polyposis;Lazard;Presse Med,2007
4. Impact of intranasal budesonide on immune inflammatory responses and epithelial remodeling in chronic upper airway inflammation;Mastruzzo;J Allergy Clin Immunol,2003
5. Myofibroblast accumulation induced by transforming growth factor-beta is involved in the pathogenesis of nasal polyps;Wang;Laryngoscope,1997
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