Accelerated throughput metabolic route screening in early drug discovery using high-resolution liquid chromatography/quadrupole time-of-flight mass spectrometry and automated data analysis-Reference-Cited by-同舟云学术

Accelerated throughput metabolic route screening in early drug discovery using high-resolution liquid chromatography/quadrupole time-of-flight mass spectrometry and automated data analysis

Published:2005 Issue:18 Volume:19 Page:2659-2670
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

Mortishire-Smith Russell J.,O'Connor Desmond,Castro-Perez Jose M.,Kirby Jane

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference26 articles.

1. , . In High-Throughput ADMETox Estimation, (eds). BioTechniques Press: Westborough, MA, 2002; 49-67.

2. Automated quantitative and qualitative analysis of metabolic stability: A process for compound selection during drug discovery

3. Liquid chromatography/tandem mass spectrometric quantification with metabolite screening as a strategy to enhance the early drug discovery process

4. Chemical Image Fusion. The Synergy of FT-NIR and Raman Mapping Microscopy To Enable a More Complete Visualization of Pharmaceutical Formulations

Cited by 124 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The photo- and microbial degradation kinetics and pathways of sulfadoxine in seawater elucidated by liquid chromatography coupled with time-of-flight mass spectrometry;Chemosphere;2024-03

2. Reverse Engineering of Medicinal and Nutritional Products - Approaches Available for Generic Product Development;Current Analytical Chemistry;2023-02

3. High-Throughput Metabolic Soft-Spot Identification in Liver Microsomes by LC/UV/MS: Application of a Single Variable Incubation Time Approach;Molecules;2022-11-20

4. Accelerating Metabolite Identification Mass Spectrometry Technology Drives Metabolite Identification Studies Forward;Drug Metabolism Handbook;2022-11-18

5. A discovery biotransformation strategy: combining in silico tools with high-resolution mass spectrometry and software-assisted data analysis for high-throughput metabolism;Xenobiotica;2022-08-03