Synthesis of di-docosahexaenoyl (C22:6)-bis(monoacylglycerol) phosphate in unlabelled and C-13 labelled forms for use as a biomarker of drug induced phospholipidosis-Reference-Cited by-同舟云学术

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Synthesis of di-docosahexaenoyl (C22:6)-bis(monoacylglycerol) phosphate in unlabelled and C-13 labelled forms for use as a biomarker of drug induced phospholipidosis

Published:2019-05-07 Issue:11 Volume:62 Page:695-706
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J Label Compd Radiopharm

Author:

Hickey Michael J.¹,Lindqvist Johnny²,Ha Young- Hwan³,Andersson Håkan²,Elmore Charles S.⁴^ORCID

Affiliation:

1. Early Chemical Development, Pharmaceutical Sciences, IMED Biotech Unit; AstraZeneca; Cambridge UK

2. Translational Biomarker & Bioanalysis, Drug Safety and Metabolism, IMED Biotech Unit; AstraZeneca; Gothenburg Sweden

3. Radio Labeling Division, Small Molecule Unit; Curachem, Inc; Korea

4. Early Chemical Development, Pharmaceutical Sciences, IMED Biotech Unit; AstraZeneca; Gothenburg Sweden

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jlcr.3714/fullpdf

Reference14 articles.

1. Generalized phospholipidosis induced by an amphiphilic cationic psychotropic drug;Robison;Toxicol Pathol,1985

2. Drug-induced phospholipidosis;Anderson;FEBS Lett,2006

3. Lysosomotropic agents;De Duve;Biochem Pharmacol,1974

4. Cationic amphiphilic drug-induced phospholipidosis;Halliwell;Toxicol Pathol,1997

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