Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes-Reference-Cited by-同舟云学术

Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes

Published:2019-04-03 Issue:5 Volume:62 Page:202-208
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J Label Compd Radiopharm

Author:

Gan Xinmin¹²,Wilson Michael W.¹²,Beyett Tyler S.³⁴,Wen Bo⁵,Sun Duxin⁵,Larsen Scott D.¹²,Tesmer John J.G.⁶⁷,Saltiel Alan R.⁸⁹,Showalter Hollis D.¹²^ORCID

Affiliation:

1. Department of Medicinal Chemistry; University of Michigan; Ann Arbor Michigan USA

2. Vahlteich Medicinal Chemistry Core; University of Michigan; Ann Arbor Michigan USA

3. Program in Chemical Biology; University of Michigan; Ann Arbor Michigan USA

4. Life Sciences Institute, Departments of Pharmacology and Biological Chemistry; University of Michigan; Ann Arbor MI United States

5. Department of Pharmaceutical Sciences; University of Michigan; Ann Arbor Michigan USA

6. Department of Biological Sciences; Purdue University; West Lafayette Indiana USA

7. Department of Medicinal Chemistry and Molecular Pharmacology; Purdue University; West Lafayette Indiana USA

8. Department of Medicine, Institute for Diabetes and Metabolic Health; University of California San Diego; San Diego California USA

9. Department of Pharmacology, Institute for Diabetes and Metabolic Health; University of California San Diego; San Diego California USA

Funder

National Institutes of Health

U.S. Department of Education

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jlcr.3716/fullpdf

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