A Molecular Analysis of the Shared Epitope Hypothesis: Binding of Arthritogenic Peptides to DRB1*04 Alleles

Author:

Anderson Kirsten M.1,Roark Christina L.1,Portas Mary1,Aubrey Michael T.1,Rosloniec Edward F.2,Freed Brian M.1

Affiliation:

1. ClinImmune Labs and University of Colorado Anschutz Medical Campus; Aurora

2. Memphis VA Medical Center; Memphis Tennessee

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

Reference34 articles.

1. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: part II;Lawrence;Arthritis Rheum,2008

2. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: part I;Helmick;Arthritis Rheum,2008

3. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis;Raychaudhuri;Nat Genet,2012

4. The shared epitope hypothesis: an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis;Gregersen;Arthritis Rheum,1987

5. New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility [published erratum appears in Arthritis Rheum 2005;52:3659];Tezenas du Montcel;Arthritis Rheum,2005

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