Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally-derived or not

Author:

Zhou Yizhou1,Shaw David1ORCID,Lam Cynthia1,Tsukuda Joni1,Yim Mandy1,Tang Danming1,Louie Salina1,Laird Michael W.1,Snedecor Brad1,Misaghi Shahram1ORCID

Affiliation:

1. Early Stage Cell Culture (ESCC) Department; Genentech, Inc., 1 DNA Way; South San Francisco California 94080

Publisher

Wiley

Subject

Biotechnology

Reference25 articles.

1. Biopharmaceutical benchmarks 2014;Walsh;Nat Biotechnol.,2014

2. Advances in Mammalian cell line development technologies for recombinant protein production;Lai;Pharmaceuticals (Basel).,2013

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4. 2007

5. 2013

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