Molybdenum Cofactor Catabolism Unravels the Physiological Role of the Drug Metabolizing Enzyme Thiopurine S‐Methyltransferase-Reference-Cited by-同舟云学术

Molybdenum Cofactor Catabolism Unravels the Physiological Role of the Drug Metabolizing Enzyme Thiopurine S‐Methyltransferase

Published:2022-05-31 Issue:4 Volume:112 Page:808-816
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharma and Therapeutics

Author:

Pristup Julika¹,Schaeffeler Elke²³,Arjune Sita¹,Hofmann Ute²,Angel Santamaria‐Araujo Jose¹,Leuthold Patrick²,Friedrich Nele⁴⁵,Nauck Matthias⁴⁵,Mayr Simon¹,Haag Mathias²,Muerdter Thomas²,Marner Franz‐Josef¹,Relling Mary V.⁶⁷,Evans William E.⁶⁷,Schwarz Guenter¹⁸,Schwab Matthias²³⁹

Affiliation:

1. Institute of Biochemistry Department of Chemistry University of Cologne Cologne Germany

2. Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology Stuttgart Germany

3. Cluster of Excellence iFIT (EXC2180) “Image‐Guided and Functionally Instructed Tumor Therapies” University of Tuebingen Tuebingen Germany

4. Institute of Clinical Chemistry and Laboratory Medicine University Medicine Greifswald Greifswald Germany

5. DZHK (German Centre for Cardiovascular Research) Partner Site Greifswald University Medicine Greifswald Germany

6. Hematological Malignancies Program St. Jude Children’s Research Hospital Memphis Tennessee USA

7. Department of Pharmaceutical Sciences St. Jude Children’s Research Hospital Memphis Tennessee USA

8. Center for Molecular Medicine Cologne (CMMC) University of Cologne Cologne Germany

9. Departments of Clinical Pharmacology Pharmacy and Biochemistry University Tuebingen Tuebingen Germany

Funder

Deutsche Forschungsgemeinschaft

National Cancer Institute

American Lebanese Syrian Associated Charities

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2637

Reference42 articles.

1. Molybdenum cofactors, enzymes and pathways

2. The Mononuclear Molybdenum Enzymes

3. Molybdenum cofactor biology, evolution and deficiency

4. Molybdenum cofactor biosynthesis and deficiency

5. Molybdenum cofactor-deficient mice resemble the phenotype of human patients

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