Validation of trail making test part A for cognitive screening in multiple sclerosis

Author:

Sayed Amira1,Abdelhadi Ghada1,Ramadan Ismail1,Galeel Aya Abdel1,Hamed Mervat1

Affiliation:

1. Dr Sayed is an Assistant Lecturer in Neurology; Dr Abdelhadi and Dr Ramadan are Professors of Neurology; Dr Galeel is a Lecturer in Radiology, and Dr Hamed is an Assistant Professor of Neurology; all authors are at Alexandria University, Egypt.

Abstract

Cognitive impairment is a crucial early and late complaint in multiple sclerosis (MS). The exact onset of cognitive impairment in MS and its pathophysiology remain elusive. A simple, easy, and time saving method is crucial for detecting early cognitive complaints, specifically information processing speed, which is important for the functionality of higher cognitive processes. Here, the authors compare the sensitivity and specificity of trail making test part A as a short and free valid test with the symbol digit modality test (SDMT) for assessment of information processing speed in a sample of Egyptian people with MS.

Publisher

Wiley

Subject

Psychiatry and Mental health,Neurology (clinical),Neurology,Pshychiatric Mental Health

Reference21 articles.

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2. Diagnosing ‘transition’ to secondary progressive multiple sclerosis (SPMS): A step‐by‐step approach for clinicians;Hamdy E;Mult Scler Relat Disord,2022

3. Symbol Digit Modalities Test: A valid clinical trial endpoint for measuring cognition in multiple sclerosis;Strober L;Mult Scler,2019

4. The Trail Making Test;Llinas‐Regla J;Assessment,2017

5. Trail Making Test errors in normal aging, mild cognitive impairment, and dementia;Ashendorf L;Arch Clin Neuropsychol,2008

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