Determination of tubuloside B by LC-MS/MS and its application to a pharmacokinetic study in rats

Author:

Yang Shenbao1,Qu Ruiying1,Sun Peilu234,Xiong Shan234,Yan Siyi5ORCID,Deng Zhipeng234ORCID

Affiliation:

1. Jiaozhou People's Hospital; Qingdao China

2. Shandong Academy of Medical Sciences; Institute of Materia Medica; Jinan China

3. Key Laboratory for Biotech-Drugs Ministry of Health; Jinan China

4. Key Laboratory for Rare and Uncommon Diseases of Shandong Province; Jinan China

5. Department of Anesthesiology; Beijing Tsinghua Changgung Hospital; Beijing China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference14 articles.

1. Tubuloside B rescues the PC12 neuronal cells from H2O2-induced apoptosis;Deng;Chinese Journal of Pathophysiology,2008

2. Protective effect of tubuloside B on TNFα-induced apoptosis in neuronal cells;Deng;Acta Pharmacologica Sinica,2004

3. European Medicines Agency 2011   Guideline on Bioanalytical Method Validation http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2011/08/WC500109686.pdf

4. Structural characterisation and identification of phenylethanoid glycosides from Cistanches deserticola;Han;Phytochemical Analysis,2012

5. Differentiation of Herba Cistanchesby fingerprint with high-performance liquid chromatography-diode array detection-mass spectrometry;Jiang;Journal of Chromatography A,2009

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