Synthesis and Biological Evaluation of 1,3,3,4-Tetrasubstituted Pyrrolidine CCR5 Receptor Antagonists. Discovery of a Potent and Orally Bioavailable Anti-HIV Agent-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of 1,3,3,4-Tetrasubstituted Pyrrolidine CCR5 Receptor Antagonists. Discovery of a Potent and Orally Bioavailable Anti-HIV Agent

Published:2007-02-12 Issue:2 Volume:2 Page:187-193
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Ma Dawei,Yu Shanghai,Li Ben,Chen Li,Chen Renhai,Yu Kunqian,Zhang Linqi,Chen Zhiwei,Zhong Dafang,Gong Zheng,Wang Renxiao,Jiang Hualiang,Pei Gang

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference22 articles.

1. New Approaches toward Anti-HIV Chemotherapy

2. Discovery and Development of Small-Molecule Chemokine Coreceptor CCR5 Antagonists

3. Unraveling the Chemistry of Chemokine Receptor Ligands

4. A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

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