Fine‐Tuning TLR‐7‐Based Therapy for Functional HBV Cure
Author:
Affiliation:
1. Emerging Infectious Diseases Program Duke‐NUS Medical School Singapore
2. Singapore Immunology Network Singapore Agency for Science, Technology and Research (A*STAR) Singapore
Funder
National Medical Research Council
Publisher
Wiley
Subject
General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/hep4.1420
Reference10 articles.
1. The role of innate immunity in the immunopathology and treatment of HBV infection
2. GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees
3. Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B
4. Safety, efficacy and pharmacodynamics of vesatolimod (GS-9620) in virally suppressed patients with chronic hepatitis B
5. TLR7 Agonist Increases Responses of Hepatitis B Virus–Specific T Cells and Natural Killer Cells in Patients With Chronic Hepatitis B Treated With Nucleos(T)Ide Analogues
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