Genomic features, evolutionary patterns and minimal residual disease at surgical margins as novel prognostic/predictive biomarkers in locally advanced rectal cancer

Author:

He Kewen1ORCID,Li Li1,Li Aijie2,Xu Yang3ORCID,Pang Jiaohui3,Mu Dianbin4,Ma Jie5,Ge Hong6,Maleki Aurian78,Qin Xueting910,Zhang Xian3,Ou Qiuxiang3,Shao Yang311,Yu Jinming1,Yuan Shuanghu1ORCID

Affiliation:

1. Department of Radiation Oncology Shandong First Medical University and Shandong Academy of Medical Sciences Shandong Cancer Hospital and Institute Jinan China

2. Shanghe County People's Hospital Jinan China

3. Geneseeq Research Institute Nanjing Geneseeq Technology Inc. Nanjing China

4. Department of Pathology Shandong Cancer Hospital and Institute Shandong First Medical University and Shandong Academy of Medical Sciences Jinan China

5. Department of Pathology The Affiliated Cancer Hospital of Zhengzhou University Zhengzhou China

6. Department of Radiation Oncology The Affiliated Cancer Hospital of Zhengzhou University Zhengzhou China

7. Department of Radiation Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA

8. Department of Chemistry Rice University Houston Texas USA

9. School of Medicine Nankai University Tianjin China

10. Department of Bio‐therapeutic the First Medical Center Chinese PLA General Hospital Beijing China

11. School of Public Health Nanjing Medical University Nanjing China

Funder

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

Reference10 articles.

1. Increasing Disparities in the Age-Related Incidences of Colon and Rectal Cancers in the United States, 1975-2010

2. Rectal Cancer, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology

3. Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer;De Caluwé L;Cochrane Database Syst Rev,2013

4. Pre‐operative chemoradiation for non‐metastatic locally advanced rectal cancer;McCarthy K;Cochrane Database Syst Rev,2012

5. Update in version 2021 of CSCO guidelines for colorectal cancer from version 2020

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