Effect of OATP1B1/1B3 Inhibitor GDC-0810 on the Pharmacokinetics of Pravastatin and Coproporphyrin I/III in Healthy Female Subjects-Reference-Cited by-同舟云学术

Effect of OATP1B1/1B3 Inhibitor GDC-0810 on the Pharmacokinetics of Pravastatin and Coproporphyrin I/III in Healthy Female Subjects

Published:2018-05-22 Issue:11 Volume:58 Page:1427-1435
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Liu Lichuan¹,Cheeti Sravanthi¹,Yoshida Kenta¹,Choo Edna²,Chen Eugene²,Chen Buyun²,Gates Mary³,Singel Stina³,Morley Roland⁴,Ware Joseph¹,Sahasranaman Srikumar¹

Affiliation:

1. Clinical Pharmacology; Genentech Inc.; South San Francisco CA USA

2. Drug Metabolism and Pharmacokinetics; Genentech Inc.; South San Francisco CA USA

3. Early Clinical Development; Genentech Inc.; South San Francisco CA USA

4. Clinical Safety; Genentech Inc.; South San Francisco CA USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcph.1261/fullpdf

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3. Food and Drug Administration Guidance for industry: clinical drug interaction studies-study design, data analysis, and clinical implications https://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM292362.pdf 2018

4. The application of physiologically based pharmacokinetic modeling to predict the role of drug transporters: scientific and regulatory perspectives;Pan;J Clin Pharmacol,2016

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