Single‐Cell, Single‐Nucleus, and Spatial RNA Sequencing of the Human Liver Identifies Cholangiocyte and Mesenchymal Heterogeneity

Author:

Andrews Tallulah S.1,Atif Jawairia12,Liu Jeff C.34,Perciani Catia T.125,Ma Xue‐Zhong1,Thoeni Cornelia5,Slyper Michal6,Eraslan Gökcen6,Segerstolpe Asa6,Manuel Justin1,Chung Sai1,Winter Erin1,Cirlan Iulia7,Khuu Nicholas7,Fischer Sandra5,Rozenblatt‐Rosen Orit6,Regev Aviv689,McGilvray Ian D.1,Bader Gary D.34,MacParland Sonya A.125ORCID

Affiliation:

1. Ajmera Transplant CentreToronto General Research InstituteUniversity Health Network Toronto ON Canada

2. Department of Immunology University of TorontoMedical Sciences Building1 King’s College Circle Toronto ON Canada

3. Department of Molecular Genetics University of Toronto Toronto ON Canada

4. The Donnelly Centre Toronto ON Canada

5. Department of Laboratory Medicine and Pathobiology University of Toronto Toronto ON Canada

6. Klarman Cell ObservatoryBroad Institute of Harvard and MIT Cambridge MA USA

7. Princess Margaret Genome Centre University Health Network Toronto ON Canada

8. Howard Hughes Medical InstituteChevy Chase MD USA

9. Koch Institute for Integrative Cancer Research Department of Biology Massachusetts Institute of Technology Cambridge MA USA

Funder

Chan Zuckerberg Initiative

Publisher

Wiley

Subject

Hepatology

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