Preclinical evaluation of point-of-care prothrombin time as a biomarker test to guide prothrombin replacement therapy in coagulopathic bleeding-Reference-Cited by-同舟云学术

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Preclinical evaluation of point-of-care prothrombin time as a biomarker test to guide prothrombin replacement therapy in coagulopathic bleeding

Published:2017-08-02 Issue:2 Volume:1 Page:252-258
ISSN:2475-0379
Container-title:Research and Practice in Thrombosis and Haemostasis
language:en
Short-container-title:Res Pract Thromb Haemost

Author:

Balendran Clare A.¹^ORCID,Henderson Neil¹,Olsson Marita²,Lövgren Ann³,Hansson Kenny M.⁴

Affiliation:

1. Personalised Healthcare & Biomarkers; Innovative Medicines and Early Biotech Unit; AstraZeneca; Mölndal Sweden

2. Early Clinical Development, Innovative Medicines and Early Development Biotech Unit; AstraZeneca; Mölndal Sweden

3. Leaflet Biotech Consulting; Solna Sweden

4. Cardiovascular and Metabolic Diseases; Innovative Medicines and Early Development Biotech Unit; AstraZeneca; Mölndal Sweden

Funder

AstraZeneca R&D Gothenburg

Publisher

Wiley

Subject

Hematology

Reference27 articles.

1. Epidemiology of urban trauma deaths: a comprehensive reassessment 10 years later;Cothren;World J Surg,2007

2. Fibrinogen substitution improves whole blood clot firmness after dilution with hydroxyethyl starch in bleeding patients undergoing radical cystectomy: a randomized, placebo-controlled clinical trial;Fenger-Eriksen;J Thromb Haemost,2009

3. Hemostatic factors and replacement of major blood loss with plasma-poor red cell concentrates;Hiippala;Anesth Analg,1995

4. Prothrombin complex concentrate and recombinant prothrombin alone or in combination with recombinant factor X and FVIIa in dilutional coagulopathy: a porcine model;Mitterlechner;J Thromb Haemost,2011

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