PGE2‐EP2/EP4 axis: A new perspective on cancer immunotherapy-Reference-Cited by-同舟云学术

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PGE₂‐EP₂/EP₄ axis: A new perspective on cancer immunotherapy

Published:2024-09 Issue:3 Volume:3 Page:
ISSN:2769-6448
Container-title:MedComm – Oncology
language:en
Short-container-title:MedComm – Oncology

Author:

Chen Lin¹²,Xu Yu‐Xin¹²,Zhou Jian‐Liang¹²^ORCID

Affiliation:

1. School of Pharmacy, Hangzhou Normal University Hangzhou Zhejiang China

2. Key Laboratory of Elemene Class Anti‐Cancer Chinese Medicines, Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province Hangzhou Normal University Hangzhou Zhejiang China

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/mog2.90

Reference5 articles.

1. PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells

2. Crosstalk between macrophage-derived PGE₂ and tumor UHRF1 drives hepatocellular carcinoma progression

3. PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment

4. PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function

5. Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment

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