Biochanin‐A has antidiabetic, antihyperlipidemic, antioxidant, and protective effects on diabetic nephropathy via suppression of TGF‐β1 and PAR‐2 genes expression in kidney tissues of STZ‐induced diabetic rats

Author:

Amri Jamal123,Alaee Mona13,Babaei Rasool1,Salemi Zahra4,Meshkani Reza2,Ghazavi Ali5,Akbari Ahmad1,Salehi Mehdi1

Affiliation:

1. Traditional and Complementary Medicine Research Center, Department of Traditional medicine, School of Medicine Arak University of Medical Sciences Arak Iran

2. Department of Clinical Biochemistry Faculty of Medicine Tehran University of Medical Sciences Tehran Iran

3. Students’ Scientific Research Center Tehran University of Medical Sciences Tehran Iran

4. Department of Biochemistry and Genetics Arak University of Medical Sciences Arak Iran

5. Department of Immunology & Microbiology, School of Medicine Arak University of Medical Sciences Arak Iran

Publisher

Wiley

Subject

Process Chemistry and Technology,Drug Discovery,Applied Microbiology and Biotechnology,Biomedical Engineering,Molecular Medicine,General Medicine,Bioengineering,Biotechnology

Reference38 articles.

1. Effect of Artemisia absinthium ethanolic extract on oxidative stress markers and the TLR4, S100A4, Bax and Bcl‐2 genes expression in the kidney of STZ‐induced diabetic rats;Bagheri F;Horm Mol Biol Clin Investig,2020

2. Free serum sorbitol and its interaction with caffeine: a suggestive approach for plausible remediation of diabetic neuropathy;Srivastava B;Biotechnol Appl Biochem,2020

3. Diabetes mellitus and renal failure: prevention and management;Nasri H;J Res Med Sci,2015

4. Diabetic kidney disease: a report from an ADA Consensus Conference;Tuttle KR;Am J Kidney Dis,2014

5. Transforming growth factor‐β1 and diabetic nephropathy;Chang AS;Am J Physiol Renal Physiol,2016

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