Bioequivalence and Pharmacokinetic Evaluation of 2 Pyrazinamide Formulations in Healthy Chinese Adults: A Single‐Dose, Open‐Label, Randomized‐Sequence, 2×2 Crossover Study

Author:

Wang Siyang1,Ren Jian1,Wang Hongxia1,Zhi Tingting1,Zhu Yuanyuan1,Feng Jinxin2,Li Zhen2,Zhang Ruiqin1

Affiliation:

1. Department of Pharmacy Second Hospital of Shanxi Medical University Taiyuan China

2. School of Pharmacy Shanxi Medical University Taiyuan China

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Reference10 articles.

1. Simultaneous determination of pyrazinamide, rifampicin, ethambutol, isoniazid and acetyl isoniazid in human plasma by LC‐MS/MS method;Luyen LT;J App Pharm Sci,2018

2. Evaluation of bioequivalence of isoniazid and pyrazinamide in three and four drugs fixed dose combinations using WHO simplified protocol;Panchagnula R;Pharmacol Res,2003

3. An improved LC‐MS/MS method for the simultaneous determination of pyrazinamide, pyrazinoic acid and 5‐hydroxy pyrazinoic acid in human plasma for a pharmacokinetic study;Shah PA;J Chromatogr B Analyt Technol Biomed Life Sci,2016

4. Protein binding of first‐line antituberculosis drugs;Alghamdi WA;Antimicrob Agents Chemother,2018

5. Pyrazinamide pharmacokinetics and efficacy in adults and children;Donald PR;Tuberculosis (Edinb),2012

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