Sample size re‐estimation in Phase 2 dose‐finding: Conditional power versus Bayesian predictive power-Reference-Cited by-同舟云学术

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Sample size re‐estimation in Phase 2 dose‐finding: Conditional power versus Bayesian predictive power

Published:2022-11-23 Issue:2 Volume:22 Page:349-364
ISSN:1539-1604
Container-title:Pharmaceutical Statistics
language:en
Short-container-title:Pharmaceutical Statistics

Author:

Liu Qingyang¹,Hu Guanyu²^ORCID,Ye Binqi³,Wang Susan⁴,Wu Yaoshi¹^ORCID

Affiliation:

1. Department of Statistics University of Connecticut Storrs Connecticut USA

2. Department of Statistics University of Missouri ‐ Columbia Columbia Missouri USA

3. Boehringer Ingelheim (China) Shanghai China

4. Boehringer‐Ingelheim Pharmaceutical Inc. Ridgefield Connecticut USA

Funder

National Science Foundation

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology,Statistics and Probability

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pst.2275

Reference36 articles.

1. Interim analyses for monitoring clinical trials that do not materially affect the type I error rate

2. Simple procedures for blinded sample size adjustment that do not affect the type I error rate

3. Blinded sample size reassessment in non-inferiority and equivalence trials

4. Adaptive Design: Results of 2012 Survey on Perception and Use

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1. A seamless phase II/III design with dose optimization for oncology drug development;Statistics in Medicine;2024-06-06

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