Irreversible aggregation of recombinant bovine granulocyte-colony stimulating factor (bG-CSF) and implications for predicting protein shelf life

Author:

Roberts Christopher J.,Darrington Richard T.,Whitley Maureen B.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference47 articles.

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3. Mechanisms of protein stabilization during freeze-drying and storage: The relative importance of thermodynamic stabilization and glassy state relaxation dynamics;Pikal,1999

4. Minimization of recombinant human Flt3 ligand aggregation at the Tm plateau: A matter of thermal reversibility;Remmele;Biochemistry,1999

5. Conformational origin of aggregation of recombinant human growth factor VIII;Grillo;Biochemistry,2001

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