A comprehensive analysis of polymorphic variants in steroid hormone and insulin-like growth factor-1 metabolism and risk of in situ breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium

Author:

Barrdahl Myrto1ORCID,Canzian Federico2ORCID,Gaudet Mia M.3,Gapstur Susan M.3,Trichopoulou Antonia4,Tsilidis Kostas56,van Gils Carla H.7,Borgquist Signe89ORCID,Weiderpass Elisabete10111213,Khaw Kay-Tee14,Giles Graham G.151617,Milne Roger L.1516,Le Marchand Loic18,Haiman Christopher19,Lindström Sara20,Kraft Peter21,Hunter David J.21,Ziegler Regina22,Chanock Stephen J.2223,Yang Xiaohong R.22,Buring Julie E.2425,Lee I-Min2425,Kaaks Rudolf1ORCID,Campa Daniele26ORCID

Affiliation:

1. Division of Cancer Epidemiology; German Cancer Research Center (DKFZ); Heidelberg Germany

2. Genomic Epidemiology Group; German Cancer Research Center (DKFZ); Heidelberg Germany

3. Epidemiology Research Program; American Cancer Society; Atlanta GA

4. Hellenic Health Foundation; Athens, Greece

5. Department of Hygiene and Epidemiology; University of Ioannina School of Medicine; Ioannina Greece

6. Department of Epidemiology and Biostatistics; School of Public Health, Imperial College London; London United Kingdom

7. Department of Epidemiology, Julius Center for Health Sciences and Primary Care; University Medical Center Utrecht; Utrecht The Netherlands

8. Clinical Trial Unit; Skåne University Hospital; Lund Sweden

9. Division of Oncology and Pathology; Clinical Sciences, Lund, Lund University; Sweden

10. Department of Community Medicine, Faculty of Health Sciences; University of Tromsø, The Arctic University of Norway; Tromsø Norway

11. Department of Research; Cancer Registry of Norway, Institute of Population-Based Cancer Research; Oslo Norway

12. Department of Medical Epidemiology and Biostatistics; Karolinska Institutet; Stockholm Sweden

13. Genetic Epidemiology Group; Folkhälsan Research Center; Helsinki Finland

14. Department of Public Health and Primary Care, School of Clinical Medicine; Addenbrooke's Hospital, University of Cambridge; Cambridge United Kingdom

15. Cancer Epidemiology Centre; Cancer Council Victoria; Melbourne VIC Australia

16. Centre for Epidemiology and Biostatistics, School of Population and Global Health; The University of Melbourne; VIC Australia

17. Faculty of Medicine; Monash University; Melbourne VIC Australia

18. Cancer Research Center of Hawaii; University of Hawaii; Honolulu HI

19. Department of Preventive Medicine; Keck School of Medicine, University of Southern California; Los Angeles CA

20. Department of Epidemiology; University of Washington; Public Health Sciences Division, Fred Hutchinson Cancer Research Center; Seattle WA

21. Program in Genetic Epidemiology and Statistical Genetics; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue; Boston MA

22. Division of Cancer Epidemiology and Genetics; National Cancer Institute; Pike Bethesda MD

23. Core Genotyping Facility, Frederick National Laboratory for Cancer Research; Gaithersburg MD

24. Divisions of Preventive Medicine, Department of Medicine; Brigham and Women's Hospital and Harvard Medical School; Boston MA

25. Department of Epidemiology; Harvard T.H. Chan School of Public Health; Boston MA

26. Department of Biology; University of Pisa; Pisa Italy

Funder

NHMRC

Hellenic Health foundation

VicHealth

Cancer Council Victoria

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference32 articles.

1. Ductal carcinoma in situ, complexities and challenges;Leonard;J Natl Cancer Inst,2004

2. Cancer statistics: breast cancer in situ;Ward;Cancer J Clin,2015

3. Risk factors for carcinoma in situ of the breast;Trentham-Dietz;Cancer Epidemiol Biomarkers Prev,2000

4. Genetic risk variants associated with in situ breast cancer;Campa;Breast Cancer Res,2015

5. Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer;Michailidou;Nat Genet,2015

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