Intratumoral infiltrating lymphocytes correlate with improved survival in colorectal cancer patients: Independent of oncogenetic features

Author:

Nazemalhosseini‐Mojarad Ehsan1ORCID,Mohammadpour Somayeh2,Torshizi Esafahani Amir2,Gharib Ehsan2,Larki Pegah2,Moradi Afshin3,Amin Porhoseingholi Mohammad1,Asadzade Aghdaei Hamid2,Kuppen Peter J. K.4,Zali Mohammad Reza1

Affiliation:

1. Gastrointestinal (GI) cancer Department, Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences Tehran Iran

2. Molecular Medicine Department, Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Live Diseases, Shahid Beheshti University of Medical Sciences Tehran Iran

3. Department of Pathology Shohada Hospital, Shahid Beheshti University of Medical Sciences Tehran Iran

4. Department of Surgery Leiden University Medical Center Leiden The Netherlands

Funder

National Institute for Medical Research Development

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference44 articles.

1. Prognostic and Predictive Values of the Immunoscore in Patients with Rectal Cancer

2. Intraepithelial CD8+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: possible association with suppression of micrometastasis

3. Phenotypic analysis of T cells infiltrating colon cancers: Correlations with oncogenetic status

4. Colorectal cancer prognosis depends on T-cell infiltration and molecular characteristics of the tumor

5. Update on tumor‐infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the international Immuno‐Oncology Biomarker Working Group on Breast Cancer;Dieci M. V.;Seminars in Cancer Biolog,2017

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