Assessing the diversity and determinants of health‐related quality of life measures in patients with acute heart failure

Author:

Patil Dhrumil12,Tang Hsin‐Ju3ORCID,Kuo Fang‐Hsiu4,Toh Han Siong567,Yang I‐Ning89,Chang Wei‐Ting4,Lee Mei‐Chuan101112,Chung Kai‐Ning4,Huang Chi‐Ya8,Hsu Wan‐Hsuan13,Chang Ting‐Chia14,Shih Jhih‐Yuan47,Liao Chia‐Te15

Affiliation:

1. Baroda Medical College Vadodara India

2. World Youth Heart Federation Vadodara India

3. Department of Nursing Chang Gung University of Science and Technology, Chronic Diseases and Health Promotion Research Center Chiayi Taiwan

4. Division of Cardiology, Department of Internal Medicine Chi Mei Medical Center Tainan Taiwan

5. Department of Intensive Care Medicine Chi Mei Medical Center Tainan Taiwan

6. Institute of Clinical Medicine, College of Medicine National Cheng Kung University Tainan Taiwan

7. Department of Health and Nutrition Chia Nan University of Pharmacy and Science Tainan Taiwan

8. Division of Nephrology, Department of Internal Medicine Chi Mei Medical Center Tainan Taiwan

9. Institute of Clinical Pharmacy and Pharmaceutical Sciences National Cheng Kung University Tainan Taiwan

10. Department of Pharmacy Chi Mei Medical Center Tainan Taiwan

11. Department of Public Health, College of Medicine National Cheng Kung University Tainan Taiwan

12. Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine National Cheng Kung University Tainan Taiwan

13. Department of Internal Medicine Chi Mei Medical Center Tainan Taiwan

14. Division of Chest Medicine, Department of Internal Medicine Chi Mei Medical Center Tainan Taiwan

15. Division of Cardiovascular Medicine Chi Mei Medical Center, School of Medicine, College of Medicine, National Sun Yat‐sen University Kaohsiung Taiwan

Abstract

AbstractAimsHeart failure with reduced ejection fraction (HFrEF) significantly impacts health‐related quality of life (HR‐QoL). Existing HR‐QoL questionnaires can show inconsistencies, potentially misrepresenting patient self‐reports. This study examines the variation in HR‐QoL measurement tools for HFrEF patients, identifying related determinants.Methods and resultsWe retrospectively analysed 134 hospitalized patients with acute decompensated HFrEF at a Taiwanese tertiary centre's Heart Failure Post‐Acute‐Care (HF‐PAC) programme. Participants completed the EuroQol‐5 dimension (EQ‐5D) questionnaire, the EQ‐5D visual analogue scale (VAS), and the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Utility values were obtained from the EQ‐5D questionnaire. Demographic features were depicted using descriptive statistics, while multivariate regression was used to ascertain relationships between HR‐QoL measurements and determinants. Average scores for EQ‐5D, MLHFQ, EQ‐5D utility, and VAS were 6.1 ± 1.6, 21.8 ± 21.3, 81.7 ± 27.0, and 59.5 ± 14.6, respectively. Significant correlations were observed among the three tools. The New York Heart Association functional class showed a notable association with all tool scores. Other associations encompassed EQ‐5D with coronary artery disease, mineralocorticoid receptor antagonists, and the 6 min walk test; EQ‐5D VAS with chronic kidney disease; and MLHFQ with age.ConclusionsThis study illuminates the variance in HR‐QoL measurement tools for Taiwanese HFrEF patients. Using a range of these tools is beneficial in unveiling diverse determinants and approaching comprehensive patient‐centred care. However, for a more precise HR‐QoL assessment in Taiwanese HFrEF patients, recalibrating the EQ‐5D‐derived utility scores might be necessary, emphasizing the importance of patient‐specific considerations within the HF‐PAC programme.

Funder

Chi Mei Medical Center

Publisher

Wiley

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