ZYBT1, a potent, irreversible Bruton’s Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer

Author:

Ghoshdastidar Krishnarup1ORCID,Patel Hoshang1,Bhayani Hitesh1,Patel Ankit1,Thakkar Kinjal1,Patel Dinesh2,Sharma Manoranjan2,Singh Jaideep2,Mohapatra Jogeswar2,Chatterjee Abhijit2,Patel Dipam3,Bahekar Rajesh3,Sharma Rajiv3,Gupta Lakshmikant4,Patel Nirmal4,Giri Poonam4,Srinivas Nuggehally R.4ORCID,Jain Mukul5,Bandyopadhyay Debdutta1ORCID,Patel Pankaj R.6,Desai Ranjit C.3

Affiliation:

1. Department of Cell Biology Zydus Research Center Ahmedabad Gujarat India

2. Department of Pharmacology Zydus Research Center Ahmedabad Gujarat India

3. Department of Medicinal Chemistry Zydus Research Center Ahmedabad Gujarat India

4. Department of Pharmacokinetics Zydus Research Center Ahmedabad Gujarat India

5. Department of Pharmacology and Toxicology Zydus Research Center Ahmedabad Gujarat India

6. Zydus Research Center Ahmedabad Gujarat India

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

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