Synthesis of Novel Uracil Non-Nucleoside Derivatives as Potential Reverse Transcriptase Inhibitors of HIV-1-Reference-Cited by-同舟云学术

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Synthesis of Novel Uracil Non-Nucleoside Derivatives as Potential Reverse Transcriptase Inhibitors of HIV-1

Published:2009-11 Issue:11 Volume:342 Page:663-670
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch. Pharm. Chem. Life Sci.

Author:

El-Brollosy Nasser R.,Al-Deeb Omar. A.,El-Emam Ali A.,Pedersen Erik B.,La Colla Paolo,Collu Gabriella,Sanna Giuseppina,Loddo Roberta

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Reference31 articles.

1. Molecular Targets for AIDS Therapy

2. Targets and strategies for the antiviral chemotherapy of AIDS

3. 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

4. Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

5. In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-Dideoxyinosine

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1. Synthesis, In Silico Prediction and In Vitro Evaluation of Antimicrobial Activity, DFT Calculation and Theoretical Investigation of Novel Xanthines and Uracil Containing Imidazolone Derivatives;International Journal of Molecular Sciences;2021-10-12

2. Uracil derivatives as non-nucleoside inhibitors of viral infections;Annual Reports in Medicinal Chemistry;2021

3. The synthesis and antituberculosis activity of 5-alkynyl uracil derivatives;Bioorganic & Medicinal Chemistry Letters;2020-08

4. Combining 25-Hydroxycholesterol with an HIV Fusion Inhibitor Peptide: Interaction with Biomembrane Model Systems and Human Blood Cells;ACS Infectious Diseases;2019-02-28

5. One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines;Chemistry Central Journal;2017-07-19

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