The addition of dexamethasone to bortezomib for patients with relapsed multiple myeloma improves outcome but ongoing maintenance therapy has minimal benefit

Author:

Harrison Simon J.12,Quach Hang3,Link Emma1,Feng Huaibao4,Dean Joanne1,Copeman Michael5,Van De Velde Helgi6,Schwarer Anthony7,Baker Bartrum8,Spencer Andrew9,Catalano John10,Campbell Philip11,Augustson Bradley12,Romeril Ken13,Prince Henry Miles12

Affiliation:

1. Peter MacCallum Cancer Centre; East Melbourne Australia

2. Sir Peter MacCallum Department of Oncology; University of Melbourne; Parkville Australia

3. St Vincents Hospital; Melbourne Australia

4. Janssen Research & Development; Raritan, New Jersey

5. Janssen-Cilag Pty Ltd; Sydney Australia

6. Janssen Research & Development; Beerse Belgium

7. Box Hill Hospital; Melbourne Australia

8. Palmerston North Hospital; Palmerston North New Zealand

9. the Alfred Hospital; Melbourne Australia

10. Frankston Hospital; Melbourne Australia

11. The Andrew Love Cancer Centre; Geelong Hospital; Geelong Australia

12. Sir Charles Gairdner Hospital; Perth Australia

13. Wellington Hospital; Wellington New Zealand

Publisher

Wiley

Subject

Hematology

Reference33 articles.

1. Recent major improvement in long-term survival of younger patients with multiple myeloma;Brenner;Blood,2008

2. Improved survival in multiple myeloma and the impact of novel therapies;Kumar;Blood,2008

3. Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma;Kikuchi;Blood,2010

4. Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model;LeBlanc;Cancer Res,2002

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