Survival analysis of a comprehensive treatment strategy for internal carotid artery blowout syndrome by nasopharyngeal carcinoma

Author:

Zhao Zhouyang1ORCID,Liao Qinming2,Yang Yimei1,Ma Yue1,Lu Xiaomeng2,Qiu Qianhui3,Han Fei4,Huang Lijin1

Affiliation:

1. Department of Neurosurgery Guangdong Provincial Hospital of Chinese Medicine (Guangdong Provincial Academy of Chinese Medical Sciences) Guangzhou China

2. Department of Neurosurgery The Third Affiliated Hospital of Southern Medical University Guangzhou China

3. Department of Otolaryngology – Head and Neck Surgery Guangdong Provincial People's Hospital Guangzhou China

4. Department of Radiotherapy Sun Yat‐sen University Cancer Center (SYSUCC) Guangzhou China

Abstract

AbstractObjectiveTo retrospectively analyze the comprehensive treatment strategy for internal carotid artery blowout syndrome (CBS) by nasopharyngeal carcinoma (NPC).MethodsOf the 311 patients of NPC with carotid artery blowout syndrome admitted at our center from April 2018 to August 2022, 288 were enrolled.ResultsThe patients were divided into two groups: treatment group (266 cases) and control group (22 cases). After comprehensive treatment, the survival rate of the treatment group was significantly higher than that of the control group, especially within 6 months to the 1 year. Preventive intervention for CBS I type may have considerable benefits. And in the long run, this treatment strategy did not significantly increase the incidence of stroke in the treatment group.ConclusionThe comprehensive treatment strategy for ICA‐CBS of patients with NPC significantly reduced the mortality of asphyxia due to epistaxis, reduced the incidence of CBS during nasal endoscopy, and finally improved survival rate.

Funder

Guangdong Basic and Applied Basic Research Foundation

Publisher

Wiley

Subject

Otorhinolaryngology

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