The Pharmacokinetics of Beraprost Sodium Following Single Oral Administration to Subjects With Impaired Kidney Function

Author:

Shimamura Masahiro1,Miyakawa Jun1,Doi Masaaki2,Okada Kiyonobu2,Kurumatani Hajimu1,Mori Yoshitaka1,Oshida Keiyu3,Nakajo Ikumi4,Oikawa Keishi4,Ushigome Fumihiko5,Miyashita Aiji5,Isono Masanao1,Miyamoto Yohei1

Affiliation:

1. Pharmaceutical Clinical Research Department; Toray Industries, Inc; Tokyo Japan

2. Clinical Data Science & Quality Management Department; Toray Industries, Inc; Tokyo Japan

3. Pharmaceutical Research Laboratories; Toray Industries, Inc; Kanagawa Japan

4. Clinical Pharmacology Global Development; Astellas Pharma Inc; Tokyo Japan

5. Analysis & Pharmacokinetics Research Laboratories; Drug Discovery Research; Astellas Pharma Inc; Ibaraki Japan

Funder

Toray Industries

Astellas Pharma

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference47 articles.

1. Successful therapy of advanced arteriosclerosis obliterans with prostacyclin;Szczeklik;Lancet.,1979

2. The in vitro and ex vivo antiplatelet effect of TRK-100, a stable prostacyclin analog, in several species;Nishio;Jpn J Pharmacol,1988

3. Vasodilator actions of TRK-100, a new prostaglandin I2 analogue;Akiba;Br J Pharmacol,1986

4. Specific binding of the new stable epoprostenol analogue beraprost sodium to prostacyclin receptors on human and rat platelets;Kajikawa;Arzneimittelforschung.,1989

5. Pharmacological and clinical properties of beraprost sodium, orally active prostacyclin analogue;Nishio;Nihon Yakurigaku Zasshi.,2001

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