Patterns in metabolite profile are associated with risk of more aggressive prostate cancer: A prospective study of 3,057 matched case–control sets from EPIC

Author:

Schmidt Julie A.1ORCID,Fensom Georgina K.1,Rinaldi Sabina2ORCID,Scalbert Augustin2,Appleby Paul N.1,Achaintre David2,Gicquiau Audrey2,Gunter Marc J.2,Ferrari Pietro2,Kaaks Rudolf3,Kühn Tilman3,Boeing Heiner4,Trichopoulou Antonia5,Karakatsani Anna56,Peppa Eleni5,Palli Domenico7,Sieri Sabina8ORCID,Tumino Rosario9,Bueno‐de‐Mesquita Bas10111213,Agudo Antonio14,Sánchez Maria‐Jose1516,Chirlaque María‐Dolores151718,Ardanaz Eva151920,Larrañaga Nerea1521,Perez‐Cornago Aurora1,Assi Nada2,Riboli Elio22,Tsilidis Konstantinos K.1222,Key Timothy J.1,Travis Ruth C.1

Affiliation:

1. Cancer Epidemiology Unit, Nuffield Department of Population HealthUniversity of Oxford Oxford United Kingdom

2. International Agency for Research on Cancer Lyon France

3. Division of Cancer EpidemiologyGerman Cancer Research Center (DKFZ) Heidelberg Germany

4. Department of EpidemiologyGerman Institute of Human Nutrition (DIfE) Potsdam‐Rehbrücke Nuthetal Germany

5. Hellenic Health Foundation Athens Greece

6. 2nd Pulmonary Medicine DepartmentSchool of Medicine, National and Kapodistrian University of Athens, “ATTIKON” University Hospital Haidari Greece

7. Cancer Risk Factors and Life‐Style Epidemiology UnitInstitute for Cancer Research, Prevention and Clinical Network (ISPRO) Florence Italy

8. Epidemiology and Prevention UnitFondazione IRCCS Istituto Nazionale dei Tumori Milano Italy

9. Cancer Registry and Histopathology Department“Civic ‐ M.P.Arezzo" Hospital, Azienda Sanitaria Provinciale Di Ragusa (ASP) Ragusa Italy

10. Department for Determinants of Chronic Diseases (DCD)National Institute for Public Health and the Environment (RIVM) Bilthoven The Netherlands

11. Department of Gastroenterology and HepatologyUniversity Medical Centre Utrecht The Netherlands

12. Department of Epidemiology and BiostatisticsSchool of Public Health, Imperial College London London United Kingdom

13. Department of Social & Preventive Medicine, Faculty of MedicineUniversity of Malaya Kuala Lumpur Malaysia

14. Unit of Nutrition and Cancer, Cancer Epidemiology Research ProgramCatalan Institute of Oncology‐IDIBELL, L'Hospitalet de Llobregat Barcelona Spain

15. CIBER in Epidemiology and Public Health (CIBERESP) Madrid Spain

16. Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibs.GRANADAHospitales Universitarios de Granada/Universidad de Granada Granada Spain

17. Department of EpidemiologyRegional Health Council, IMIB‐Arrixaca Murcia Spain

18. Department of Health and Social SciencesMurcia University Murcia Spain

19. Navarra Public Health Institute Pamplona Spain

20. IdiSNA, Navarra Institute for Health Research Pamplona Spain

21. Basque Regional Health DepartmentPublic Health Division of Gipuzkoa‐BIODONOSTIA San Sebastian Spain

22. Department of Hygiene and EpidemiologyUniversity of Ioannina School of Medicine Ioannina Greece

Funder

Cancer Research UK

World Cancer Research Fund

Medical Research Council Canada

ISCIII

Health Research

National Research Council Sri Lanka

Associazione Italiana per la Ricerca sul Cancro

Bundesministerium für Bildung und Forschung

Deutsches Krebsforschungszentrum

Deutsche Krebshilfe

Federal Ministry of Education and Research

German Cancer Aid

European Commission

Centre International de Recherche sur le Cancer

Publisher

Wiley

Subject

Cancer Research,Oncology

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