Ganglioside GM3 suppresses lipopolysaccharide‐induced inflammatory responses in rAW 264.7 macrophage cells through NF‐κB, AP‐1, and MAPKs signaling

Author:

Park Junyoung1,Kwak Choong‐Hwan12,Ha Sun‐Hyung1,Kwon Kyung‐Min13,Abekura Fukushi1,Cho Seung‐Hak4,Chang Young‐Chae5ORCID,Lee Young‐Choon6,Ha Ki‐Tae2,Chung Tae‐Wook2,Kim Cheorl‐Ho1ORCID

Affiliation:

1. Molecular and Cellular Glycobiology UnitDepartment of Biological Sciences, Sungkyunkwan University, Seoburo, Jangan‐GuSuwonGyunggi‐DoRepublic of Korea

2. Division of Applied MedicineSchool of Korean Medicine, Pusan National UniversityYangsan CityGyeongsangnam‐DoRepublic of Korea

3. Research InstituteDavinch‐K Co., LtdGeumcheon‐GuSeoulRepublic of Korea

4. Division of Enteric Diseases, Center for Infectious Diseases ResearchKorea National Institute of HealthHeungdeok‐guCheongjuRepublic of Korea

5. Research Institute of Biomedical Engineering and Department of MedicineCatholic University of Daegu School of MedicineDaeguRepublic of Korea

6. Faculty of Medicinal BiotechnologyDong‐A UniversitySaha‐GuBusanRepublic of Korea

Funder

National Research Foundation of Korea

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference45 articles.

1. Chronic Inflammatory Disease and Osteopathy: A Systematic Review

2. Nitric oxide neurotoxicity in neurodegenerative diseases

3. LPS Signal Transduction: The Picture is Becoming More Complex

4. P38 and extracellular signal‐regulated kinase mitogen‐activated protein kinase pathways are required for nuclear factorkappaB p65 transactivation mediated by tumor necrosis factor;Vanden Berghe W;J Biol Chem,1998

5. Ascofuranone inhibits lipopolysaccharide–induced inflammatory response via NF-kappaB and AP-1, p-ERK, TNF-α, IL-6 and IL-1β in RAW 264.7 macrophages

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