Computational repurposing and preclinical validation of colquhounia root tablets for membranous nephropathy

Author:

Mao Xia1,Wang Kexin1,Liu Yudong1,Su Xiaohui1,Wu Anguo2,Chen Lin1,Wang Jiangrui34,Cai Beilei4,Zhang Yanqiong1ORCID,Huang Feng5,Lin Na1

Affiliation:

1. Research Center of Traditional Chinese Medicine theory and literatures Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Beijing China

2. Sichuan Key Medical Laboratory of New Drug Discovery and Druggability Evaluation Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica School of Pharmacy Southwest Medical University Luzhou China

3. Pharmceutical Factory of the Chongqing Academy of Medica Chongqing China

4. Sinomune Pharmaceutical Co. Ltd Wuxi China

5. School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization Yunnan University of Chinese Medicine Kunming China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

China Academy of Chinese Medical Sciences

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

Reference8 articles.

1. The treatment of idiopathic membranous nephropathy: A dilemma or a conundrum?

2. Clinical observation on colquhounia root tablet in treating lipid metabolism disturbance secondary to nephrotic syndrome;Wu XL;Chinese J Integr Tradit Western Med,2002

3. Clinical observation of the combination of Huoba Huagen tablets and irbesartan in the treatment of moderate proteinuria in idiopathic membranous nephropathy;Xie QK;Chinese J Integr Tradit Western Nephrol,2016

4. Chemical constituents of Tripterygium hypoglaucum;Wang F;Chinese Tradit Herbal Drugs,2011

5. Chemical constituents from the rhizomes of tripterygium hypoglaucum (II);Song Q;J Chinese Med Mater,2021

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