Modeling post‐translational modifications and cancer‐associated mutations that impact the heterochromatin protein 1α‐importin α heterodimers-Reference-Cited by-同舟云学术

Modeling post‐translational modifications and cancer‐associated mutations that impact the heterochromatin protein 1α‐importin α heterodimers

Published:2019-06-14 Issue:11 Volume:87 Page:904-916
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Zimmermann Michael T.¹²,Williams Monique M.³⁴,Klee Eric W.³⁴,Lomberk Gwen A.⁵⁶⁷,Urrutia Raul⁵⁷⁸^ORCID

Affiliation:

1. Bioinformatics Research and Development Laboratory, and Precision Medicine Simulation Unit, Genomic Science and Precision Medicine Center (GSPMC)Medical College of Wisconsin Milwaukee Wisconsin

2. Clinical and Translational Sciences InstituteMedical College of Wisconsin Milwaukee Wisconsin

3. Department of BiochemistryMayo Clinic Rochester Minnesota

4. Division of Biomedical Statistics and InformaticsMayo Clinic Rochester Minnesota

5. Division of Research, Department of SurgeryMedical College of Wisconsin Milwaukee Wisconsin

6. Department of Pharmacology and ToxicologyMedical College of Wisconsin Milwaukee Wisconsin

7. Genomic Science and Precision Medicine Center (GSPMC)Medical College of Wisconsin Milwaukee Wisconsin

8. Department of BiochemistryMedical College of Wisconsin Milwaukee Wisconsin

Funder

National Cancer Institute

National Institute of Diabetes and Digestive and Kidney Diseases

National Institutes of Health

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prot.25752

Reference77 articles.

1. HP1α guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation

2. Heterochromatin Protein 1γ Epigenetically Regulates Cell Differentiation and Exhibits Potential as a Therapeutic Target for Various Types of Cancers

3. Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression

4. Heterochromatin protein 1α: a hallmark of cell proliferation relevant to clinical oncology

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