Dantrolene rescues arrhythmogenic RYR2 defect in a patient‐specific stem cell model of catecholaminergic polymorphic ventricular tachycardia-Reference-Cited by-同舟云学术

Dantrolene rescues arrhythmogenic RYR2 defect in a patient‐specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

Published:2012-01-25 Issue:3 Volume:4 Page:180-191
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Jung Christian B.¹,Moretti Alessandra¹²,Mederos y Schnitzler Michael³,Iop Laura¹,Storch Ursula³,Bellin Milena¹,Dorn Tatjana¹,Ruppenthal Sandra⁴,Pfeiffer Sarah³,Goedel Alexander¹²,Dirschinger Ralf J.¹²,Seyfarth Melchior⁵,Lam Jason T.¹,Sinnecker Daniel¹²,Gudermann Thomas³,Lipp Peter⁴,Laugwitz Karl‐Ludwig¹²

Affiliation:

1. Klinikum rechts der Isar, Technische Universität München, I. Medizinische Klinik, Kardiologie, München, Germany

2. Deutsches Herzzentrum, Technische Universität München, Erwachsenenkardiologie, München, Germany

3. Walther‐Straub‐Institut für Pharmakologie and Toxikologie, Ludwig‐Maximilians Universität München, Goethetraße, München, Germany

4. Institut für Molekulare Zellbiologie, Medizinische Fakultät, Universitätsklinikum Homburg/Saar, Universität des Saarlandes, Homburg/Saar, Germany

5. Helios Klinikum Wuppertal‐Universität Witten‐Herdecke, III. Medizinische Klinik, Kardiologie, Wuppertal, Germany

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/emmm.201100194

Reference45 articles.

1. Cardiac calcium signalling

2. Macromolecular complexes regulating cardiac ryanodine receptor function

3. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

4. Calcium Sparks: Elementary Events Underlying Excitation-Contraction Coupling in Heart Muscle

5. From the Ryanodine Receptor to Cardiac Arrhythmias

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