Hypoxic priming of mESCs accelerates vascular‐lineage differentiation through HIF1‐mediated inverse regulation of Oct4 and VEGF

Author:

Lee Sae‐Won1,Jeong Han‐Kyul1,Lee Ji‐Young1,Yang Jimin1,Lee Eun Ju1,Kim Su‐Yeon1,Youn Seock‐Won1,Lee Jaewon1,Kim Woo Jean2,Kim Kyu‐Won34,Lim Jeong Mook5,Park Jong‐Wan6,Park Young‐Bae1,Kim Hyo‐Soo14

Affiliation:

1. Department of Internal Medicine, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea

2. National Research Laboratory of Regenerative Sexual Medicine, Department of Urology, Inha University School of Medicine, Incheon, Korea

3. Division of Pharmaceutical Biosciences, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea

4. WCU Program, Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Korea

5. WCU Biomodulation Program, Department of Agricultural Biotechnology, Seoul National University, Seoul, Korea

6. Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Korea

Publisher

EMBO

Subject

Molecular Medicine

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