V600E Braf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16 INK4a-Reference-Cited by-同舟云学术

V600E Braf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16 INK4a

Published:2010-10-13 Issue:11 Volume:2 Page:458-471
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Carragher Linda A. S.¹,Snell Kimberley R.¹,Giblett Susan M.¹,Aldridge Victoria S. S.¹,Patel Bipin¹,Cook Simon J.²,Winton Doug J.³,Marais Richard⁴,Pritchard Catrin A.¹

Affiliation:

1. Department of Biochemistry, University of Leicester, Leicester, UK

2. Laboratory of Molecular Signalling, The Babraham Institute, Babraham, Cambridge, UK

3. Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK

4. Signal Transduction Team, The Institute of Cancer Research, Cancer Research UK Centre of Cell and Molecular Biology, London, UK

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/emmm.201000099

Reference51 articles.

1. The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A–ARF locus in response to oncogene- and stress-induced senescence

2. CDKN2A Variants in a Population-Based Sample of Queensland Families With Melanoma

3. Upregulation of Wilms' tumor gene 1 (WT1) in desmoid tumors

4. Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

5. BRAF Mutations in Aberrant Crypt Foci and Hyperplastic Polyposis

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