GLI1 regulates a novel neuropilin‐2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation

Author:

Goel Hira Lal1,Pursell Bryan1,Chang Cheng1,Shaw Leslie M.1,Mao Junhao1,Simin Karl1,Kumar Prashant1,Kooi Craig W. Vander2,Shultz Leonard D.3,Greiner Dale L.4,Norum Jens Henrik5,Toftgard Rune5,Kuperwasser Charlotte6,Mercurio Arthur M.1

Affiliation:

1. Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA

2. Department of Cellular and Molecular Biochemistry, Center for Structural Biology, University of Kentucky, Lexington, KY, USA

3. The Jackson Laboratory, Bar Harbor, ME, USA

4. Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA

5. Department of Bioscience and Nutrition, Center for Biosciences, Karolinska Institute, Novum, Huddinge, Sweden

6. Department of Anatomy and Cellular Biology, Tufts University School of Medicine, Boston, MA, USA

Publisher

EMBO

Subject

Molecular Medicine

Reference87 articles.

1. Prospective identification of tumorigenic breast cancer cells

2. The evolving concept of cancer and metastasis stem cells

3. Vascular endothelial growth factor is an autocrine survival factor for neuropilin‐expressing breast carcinoma cells;Bachelder RE;Cancer Res,2001

4. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4;Bachelder RE;Cancer Res,2002

5. Competing autocrine pathways involving alternative neuropilin‐1 ligands regulate chemotaxis of carcinoma cells;Bachelder RE;Cancer Res,2003

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