Lapatinib, a dual HER1/HER2 tyrosine kinase inhibitor, augments basal cleavage of HER2 extracellular domain (ECD) to inhibit HER2-driven cancer cell growth

Author:

Vazquez-Martin Alejandro,Oliveras-Ferraros Cristina,Cufí Silvia,Del Barco Sonia,Martin-Castillo Begoña,Menendez Javier A.

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference23 articles.

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3. A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses;Cameron;Breast Cancer Res Treat,2008

4. Circulating HER2 extracellular domain and resistance to chemotherapy in advanced breast cancer;Colomer;Clin Cancer Res,2000

5. erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells;Di Fiore;Science (Washington, DC),1987

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