NF-κB-regulated miR-155, via repression of QKI, contributes to the acquisition of CSC-like phenotype during the neoplastic transformation of hepatic cells induced by arsenite

Author:

Chen Chao12,Luo Fei12,Yang Qianlei12,Wang Dapeng3,Yang Ping4,Xue Junchao12,Dai Xiangyu12,Liu Xinlu12,Xu Hui12,Lu Jiachun4,Zhang Aihua3,Liu Qizhan12ORCID

Affiliation:

1. Institute of Toxicology; School of Public Health; Nanjing Medical University; Nanjing Jiangsu People's Republic of China

2. The Key Laboratory of Modern Toxicology; Ministry of Education; School of Public Health; Nanjing Medical University; Nanjing Jiangsu People's Republic of China

3. The Key Laboratory of Environmental Pollution Monitoring and Disease Control; Ministry of Education; School of Public Health; Guizhou Medical University; Guiyang Guizhou People's Republic of China

4. The School of Public Health, Institute for Chemical Carcinogenesis; Guangzhou Medical University; Guangzhou Guangdong People's Republic China

Funder

The Natural Science Foundations of China

The Science and Technology Project of Guangzhou

The open project of the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guiyang Medical University, China

The Postgraduate Innovation Project of Jiangsu province

The Priority Academic Program Development of Jiangsu Higher Education Institutions 2014

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference47 articles.

1. Global cancer statistics;Jemal;CA Cancer J Clin,2011

2. Hepatocellular carcinoma;Forner;Lancet,2012

3. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Some drinking-water disinfectants and contaminants, including arsenic;Anders;IARC Monogr Eval Carcinog Risks Hum,2004

4. Involvement of calcium-dependent protein kinase C in arsenite-induced genotoxicity in Chinese hamster ovary cells;Liu;J Cell Biochem,1997

5. Arsenic in the aetiology of cancer;Tapio;Mutat Res,2006

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