Metformin Stimulates Intestinal Glycolysis and Lactate Release: A single‐Dose Study of Metformin in Patients With Intrahepatic Portosystemic Stent-Reference-Cited by-同舟云学术

Metformin Stimulates Intestinal Glycolysis and Lactate Release: A single‐Dose Study of Metformin in Patients With Intrahepatic Portosystemic Stent

Published:2021-08-11 Issue:5 Volume:110 Page:1329-1336
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharmacol Ther

Author:

Rittig Nikolaj¹²^ORCID,Aagaard Niels K.³,Sundelin Elias¹²^ORCID,Villadsen Gerda E.³^ORCID,Sandahl Thomas D.³^ORCID,Holst Jens J.⁴^ORCID,Hartmann Bolette⁴,Brøsen Kim⁵^ORCID,Grønbæk Henning³^ORCID,Jessen Niels¹⁶⁷^ORCID

Affiliation:

1. Steno Diabetes Center Aarhus Aarhus University Hospital Aarhus N Denmark

2. Department and Laboratories of Diabetes and Hormone diseases Aarhus University Hospital Aarhus N Denmark

3. Department of Hepatology and Gastroenterology Aarhus University Hospital Aarhus N Denmark

4. Department of Biomedical Sciences Novo Nordisk Foundation Center for Basic Metabolic ResearchUniversity of Copenhagen Copenhagen Denmark

5. Department of Public Health, Clinical Pharmacology, Pharmacy and Environmental Health University of Southern Denmark Odense Denmark

6. Department of Biomedicine Aarhus University Aarhus C Denmark

7. Department of Clinical Pharmacology Aarhus University Hospital Aarhus N Denmark

Funder

Aase og Ejnar Danielsens Fond

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2382

Reference49 articles.

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2. Metformin Biodistribution: A Key to Mechanisms of Action?

3. [11C]-Labeled Metformin Distribution in the Liver and Small Intestine Using Dynamic Positron Emission Tomography in Mice Demonstrates Tissue-Specific Transporter Dependency

4. In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution, and Kinetic Analyses

5. Efficacy and Metabolic Effects of Metformin and Troglitazone in Type II Diabetes Mellitus

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