Obeticholic acid, a selective farnesoid X receptor agonist, regulates bile acid homeostasis in sandwich-cultured human hepatocytes
Author:
Affiliation:
1. Intercept Pharmaceuticals Inc.; San Diego California
2. Qualyst Transporter Solutions; Durham North Carolina
Funder
Intercept Pharmaceuticals, Inc
Publisher
Wiley
Subject
General Pharmacology, Toxicology and Pharmaceutics,Neurology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/prp2.329/fullpdf
Reference45 articles.
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3. Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor;Ananthanarayanan;J Biol Chemist,2001
4. Changing nomenclature for PBC: from ‘cirrhosis’ to ‘cholangitis’;Beuers;Gastroenterology,2015
5. Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents;Boyer;Am J Phys Gastrointest Liver Physiol,2006
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