ProteinFlow: An advanced framework for feature engineering in protein data analysis

Author:

Mi Yanlin12ORCID,Marcu Stefan‐Bogdan1,Yallapragada Venkata V. B.3,Tabirca Sabin14

Affiliation:

1. School of Computer Science and Information Technology University College Cork Cork Ireland

2. SFI Centre for Research Training in Artificial Intelligence University College Cork Cork Ireland

3. Centre for Advanced Photonics and Process Analytics Munster Technological University Cork Ireland

4. Faculty of Mathematics and Informatics Transylvania University of Brasov Brasov Romania

Abstract

AbstractIn the burgeoning field of proteins, the effective analysis of intricate protein data remains a formidable challenge, necessitating advanced computational tools for data processing, feature extraction, and interpretation. This study introduces ProteinFlow, an innovative framework designed to revolutionize feature engineering in protein data analysis. ProteinFlow stands out by offering enhanced efficiency in data collection and preprocessing, along with advanced capabilities in feature extraction, directly addressing the complexities inherent in multidimensional protein data sets. Through a comparative analysis, ProteinFlow demonstrated a significant improvement over traditional methods, notably reducing data preprocessing time and expanding the scope of biologically significant features identified. The framework's parallel data processing strategy and advanced algorithms ensure not only rapid data handling but also the extraction of comprehensive, meaningful insights from protein sequences, structures, and interactions. Furthermore, ProteinFlow exhibits remarkable scalability, adeptly managing large‐scale data sets without compromising performance, a crucial attribute in the era of big data.

Funder

Science Foundation Ireland

Publisher

Wiley

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4. BioFeatureFinder: Flexible, unbiased analysis of biological characteristics associated with genomic regions

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